Chapter 01
What is Codeine?
What is codeine? Codeine is an opioid found in cough syrups and prescribed for pain relief after surgeries or illnesses like cancer. Often combined with acetaminophen, it comes in tablets, syrups, and liquids, widely used for pain management and cough suppression.
Once ingested, the liver converts codeine into morphine, which binds to opioid receptors in the brain. This triggers dopamine release, providing pain relief and mild euphoria. With repeated use, tolerance builds, requiring higher doses for the codeine side effects.
Dependence occurs when the body physically relies on codeine, causing withdrawal symptoms if stopped. Addiction, however, leads to compulsive drug use despite harmful consequences. Recognising this difference is crucial in preventing misuse and managing long-term risks.










