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Why Some People Are More Prone to Depression?

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Depression is a disorder that affects over 4% of the world’s population. It is a dangerous mental health condition that takes over 800,000 lives yearly. But why is it so prevalent and so dangerous?

The answer is complex but lies in the fact that it is quite difficult to identify the signs of the disorder and differentiate it from the regular periods of low mood associated with daily life. There are multiple other factors that also influence this of course, including access to healthcare services, lack of awareness, and the stigma surrounding mental health disorders.

While depression can affect anyone, research shows that some people are more at risk for the disorder than others. This blog explores why some people are more prone to depression and if there are ways to reduce the risk of incidence of the disorder. 

​​5 reasons why some people are more prone to depression?

There are multiple factors that influence the incidence of depression. These can fall under genetic, environmental, and biological causes. The six main reasons why a person could be prone to depression include:


Individuals with a close family member with depression face two to three times greater risk of developing the disorder themselves. Heritability also plays a role in the incidence with this factor playing a 40-50% role in the risk of developing the disorder. Genetics also interacts with life events like trauma leading to an additional risk for the development of depression. 

Hormonal Shifts

Hormonal shifts can also play a role in making individuals more prone to depression. Here are a few instances of how hormonal changes can influence one's susceptibility to depression:

Puberty and Adolescent Hormonal Changes: During this period, the brain undergoes substantial structural and functional changes, and these hormonal fluctuations can contribute to vulnerability to mood disorders like depression.

Menstrual Cycle and Premenstrual Dysphoric Disorder (PMDD): Women may experience mood changes and depressive symptoms in relation to their menstrual cycles. Premenstrual dysphoric disorder (PMDD) is a severe form of premenstrual syndrome (PMS) characterized by intense

mood swings, irritability, and depressive symptoms.

Postpartum Depression: After childbirth, women can experience postpartum depression, a mood disorder that occurs within the first year following delivery. The hormonal changes that accompany pregnancy, including a sudden drop in estrogen and progesterone levels after delivery, are believed to contribute to the development of postpartum depression.

If you or someone you know is experiencing depression or depressive symptoms, it is crucial to seek professional help from a healthcare provider for accurate diagnosis and appropriate treatment.

Chronic Illnesses

Living with a chronic illness or enduring persistent pain can take a toll on both the body and the mind. Beyond the physical challenges, individuals grappling with these conditions often face a heightened risk of developing depression. 

The intricate relationship between chronic illness, pain, and depression stems from many factors. The relentless nature of ongoing health issues can lead to frustration, helplessness, and a sense of loss. 

Chronic pain, in particular, can disrupt sleep patterns, limit daily activities, and erode one's overall quality of life. Additionally, the physiological changes induced by chronic illness and pain, such as inflammation and alterations in neurotransmitter levels, can directly impact mood regulation. 

The social and emotional implications, including social isolation, strained relationships, and a diminished sense of self-worth, further contribute to the vulnerability to depression. 

Childhood Trauma/Abuse

Childhood is meant to be a time of innocence, joy, and discovery. However, for those who have experienced trauma or abuse during their formative years, the impact can reverberate well into adulthood, often leading to an increased vulnerability for depression. 

The profound and lasting effects of childhood trauma stem from the fact that it disrupts the very foundation of a child's emotional and psychological development. Traumatic experiences, such as physical or emotional abuse, neglect, or witnessing violence, can reshape the brain's stress response system, leaving it hypersensitive to future challenges. 

The aftermath of such experiences often includes feelings of fear, shame, and powerlessness, which can persist long after the actual events. These unresolved emotional wounds, combined with distorted self-perceptions and impaired coping mechanisms, pave the way for the development of depressive symptoms later in life. 

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Grief is an inherent part of the human experience, a natural response to the loss of someone or something deeply cherished. While grief is a normal and necessary process, it can also become a risk factor for depression when it becomes prolonged or overwhelming. 

The emotional anguish and pain that accompany grief can shake the very foundation of our being, leaving us vulnerable to a range of complex emotions. The profound sense of emptiness, sadness, and yearning can persist far beyond what is considered a typical mourning period. 

The loss of a loved one disrupts our sense of identity and purpose, shattering the familiar rhythms of life. The prolonged state of grief can give rise to a range of depressive symptoms, including persistent sadness, loss of interest, changes in appetite and sleep patterns, and feelings of hopelessness. 

It is important to recognize that grief and depression are distinct experiences, yet they can intertwine and amplify one another. Understanding the interplay between grief and depression allows us to provide compassionate support and appropriate resources to those navigating the arduous journey of healing. 

By acknowledging the weight of loss and offering a supportive environment, we can help individuals find solace, regain resilience, and eventually embark on a path toward renewed hope.

How is depression treated?

Depression is a complex mental health condition, but the good news is that effective treatments are available to help individuals find relief and regain control of their lives. The treatment of depression typically involves a combination of therapeutic interventions, lifestyle changes, and, in some cases, medication. 

Psychotherapy, such as cognitive-behavioral therapy (CBT), is a commonly used approach that helps individuals identify and modify negative thought patterns, develop healthy coping strategies, and build resilience. 

In some instances, medication, such as selective serotonin reuptake inhibitors (SSRIs) or other antidepressants, may be prescribed to rebalance brain chemistry and alleviate symptoms. Lifestyle modifications, including regular exercise, a balanced diet, sufficient sleep, and stress management techniques, can also play a crucial role in depression treatment. 

How can you cope with Depression?

Here are some key points to consider:

  • Seek professional help: Reach out to a mental health professional who can provide an accurate diagnosis and guide you through evidence-based treatment options.
  • Build a support network: Surround yourself with understanding and supportive individuals, such as family, friends, or support groups, who can offer a listening ear and encouragement.
  • Practice self-care: Prioritize self-care activities that promote physical and emotional well-being, including regular exercise, healthy eating, sufficient sleep, and relaxation techniques such as meditation or deep breathing exercises.
  • Engage in pleasurable activities: Participate in activities you enjoy and that bring you a sense of fulfillment, such as hobbies, creative outlets, or spending time in nature.
  • Set realistic goals: Break tasks into manageable steps and set achievable goals to avoid feeling overwhelmed. Celebrate even small accomplishments as they contribute to a sense of achievement.
  • Establish a routine: Create a structured daily routine to provide a sense of stability and purpose. This can include regular sleeping and waking times, meal schedules, and engaging in activities at consistent intervals.
  • Practice stress management: Learn and utilize stress management techniques, such as deep breathing exercises, mindfulness, or engaging in activities that promote relaxation and stress reduction.
  • Limit alcohol and drug use: Substance use can worsen depression symptoms, so it's important to minimize or avoid alcohol and drug consumption.
  • Stay connected: Make an effort to maintain social connections, even if it feels challenging. Reach out to loved ones, attend social events, or consider joining support groups to combat feelings of isolation.

Remember, coping with depression is a personal journey, and it may take time to find strategies that work best for you. Be patient with yourself and don't hesitate to seek professional help when needed.

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Can depression be prevented?

While depression cannot always be completely prevented, there are proactive steps individuals can take to reduce its risk. Nurturing a healthy lifestyle, including regular exercise, balanced nutrition, and sufficient sleep, can promote mental well-being. 

Building strong social connections, seeking support when needed, and managing stress effectively are also important. Early intervention through therapy, self-care practices, and developing coping mechanisms can help mitigate the impact of stressors and potentially prevent the onset of depression. 

Remember, prevention strategies vary for each person, so it's essential to prioritize mental health and seek professional guidance when necessary.

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