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What happens in your Brain during Depression?

Brain during Depression

Depression is a serious mental condition affecting the individual’s mood, feelings, thoughts and well being. They have changed their patterns of appetite and sleep. They would be unable to experience in pleasure in any activities and would possess a sense of hopelessness, helplessness, and worthlessness. These are all the observable changes in an individual with clinical depression. These changes are the resultant of the changes in the Brain during Depression.

It is also possible that they have suicidal thoughts or ideations and also there could be few attempts at suicide in few cases. There a few changes that brain undergoes in terms of structural and functional alterations which is basically due to the chemical imbalances in the brain.

Depression causes brain damage or Brain during Depression

Structural Alteration:

Shrinkage in the certain parts of the brain- The brain regions namely hippocampus and the frontal lobe shrank among those individuals who had suffered from depression for years together.

  • Hippocampus is a part of the limbic system of the brain which is responsible for the processing the new memories in the brain for the long-term storage.
  • The frontal lobe is associated with managing the emotional reactions, focusing attention, problem-solving, judgment making and many others.

Functional alterations:

  • Increased activity in the amygdala region of the brain’s limbic system. It is associated with the regulation of emotions like sorrow, fear, anger, and pleasure.
  • There are decreased levels of mood-related chemicals namely serotonin, dopamine, and norepinephrine in the synaptic region of the neurons.

One of the possible causes for the decrease in the levels of key neurotransmitters mentioned above is because of the enzyme activity of the monoamine oxidase which breaks those chemicals.

Depression and the brain effects

Brain during Depression

Loss of serotonin and dopamines takes place at different rates among the depressed individuals. This would result in the variation in the nature, pattern, and severity of the symptoms of the brain during the depression.

  • Serotonin– Responsible for inhibiting pain and in the regulation of sleep, appetite, and mood. Low levels of serotonin lead to higher risks for suicide.
  • Dopamine– Responsible for motivation, movement, and perception of reality. Any problem in its transmission would probably result in depression associated with psychosis and/or substance abuse.
  • Norepinephrine– This helps in recognizing and responding to the stressful events and situations of life. Those with the depression, may not have proper release and transmission of the neurotransmitter. This would result in an inability to handle stress effectively.

Though there are certain changes that take place in the brain in terms of chemical imbalances, it requires many evident proofs and studies to determine the same. But these chemical changes which take place are sufficient enough to diagnose the condition. Further, the causes for the changes in the brain if found specifically, then the prevention and/or treatment would become easy.

Visit Cadabam’s to know more about the Brain during Depression,  signs and symptoms of depression and get the right treatment. Feel free to call @+91 96111 94949.

 

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