What is a Panic Attack?

A woman named Bella in her mid 30’s was once rushed to the emergency room of a nearby hospital. She was profusely sweating and she felt like her heart was racing at one instance, such that she was unable to take a breath. She and her husband were certain that, she had a heartache. But, […]

Read more
Alternative text

Internet Addiction

Do you play video games on the Internet in overabundance? Are you enthusiastically shopping online? Can’t physically quit checking Facebook? If your answer is yes for any of these questions, you may have the internet addiction.   The world which we live in today is full of advanced technological inventions. Nowadays education, entertainment, communication, and […]

Read more
Alternative text

Is Schizophrenia Genetic?

All of us are aware of how genetics plays an important role in various illnesses. But, have you ever imagined as to what has heredity to do with Schizophrenia? This is one of the common questions many people ask whether schizophrenia is a hereditary disease. The answer is yes and no! Yes, Schizophrenia does have […]

Read more
Alternative text

Guide for caregivers for Schiz...

Schizophrenia can affect an individual to an extent that they turn incapable to taking care of themselves. At this time, the role of a caregiver, family or friend, becomes important. Taking care of an individual with schizophrenia can be very difficult as they can get aggressive or rigid suddenly due to their symptoms. Medications and […]

Read more
Alternative text

Food Addiction

Is your loved one eating in excess, or even more than what is essential for their proper nutrition or a healthy living? Then, it may be a sign or indication of food addiction. Here a person perpetually engages in ravaging behaviors of overeating. This is the reason for which some people cannot sway themselves around […]

Read more
Alternative text

Tricyclic Antidepression Drugs May Harm Health More Than Treating Depression

Tricyclic antidepressants such as amitriptyline, desipramine, and doxepin, may harm your heart, according to a new study conducted by researchers at University College London (UCL). This risk may extend beyond individuals who are being treated for depression, as these older antidepressants are also used to treat anxiety, sleep problems, headache, and back pain, among other conditions.
Although tricyclic antidepressants are one of the oldest classes of antidepressants, they are still used extensively, according to eMedExpert. Today, selective serotonin reuptake inhibitors (SSRIs) have replaced tricyclics as the treatment of choice for depressive disorders, primarily because patients tolerate them better and they are safer if taken in excess.
Researchers at University College London compared the use of tricyclic antidepressants with SSRIs or no antidepressant use in nearly 15,000 individuals in Scotland. Overall, the older antidepressants were linked with a 35 percent increased risk of cardiovascular disease, while use of SSRIs was not.
Based on these findings, Dr. Mark Hamer, senior research fellow in the Department of Epidemiology and Public Health at UCL remarked that they “suggest that there is an association between the use of tricyclic antidepressants and an increased risk of CVD that is not explained by existing mental illness.” The study results thus indicate that tricyclics have properties that are responsible for the greater risk.
Previous research has shown tricyclic use to be associated with a significantly higher rate of serious cardiovascular side effects, such as increased heart rate, as well as arrhythmias, blood pressure abnormalities, and congestive heart failure. They have also been linked with weight gain and diabetes, which are risk factors for cardiovascular disease.
The UCL study’s authors note that other factors may be involved in the possible link between tricyclic antidepressant use and cardiovascular disease. Hamer pointed out that individuals who take antidepressants are more likely to be overweight, smoke, and not get sufficient exercise, also risk factors for cardiovascular disease.
Before it can be determined with more certainty that tricyclic antidepressants can harm the heart, “there needs to be more research looking closely at the effects of these drugs on your heart,” notes Amy Thompson, senior cardiac nurse at the British Heart Foundation. Because antidepressants help a great many people, “it would be unwise for anyone taking them to stop based on the results of this study alone.”

Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>

DO YOU HAVE ANY ENQUIRIES ?