Treatment for Obsessive compul...

Obsessive compulsive disorder (OCD) affects an individual’s thoughts and behaviour. Here the individual has intrusive repetitive distressing thoughts and compulsions or ritualistic mental acts or behaviour that temporarily reduces the distress. Living with OCD can be devastating as the individual is aware that something is wrong with them but are unable to control their thoughts. […]

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Is alcoholism hereditary?

Number of studies has been conducted to find if our gene is the cause of alcoholism, yet there has not been a study that confirms it. Experts have conducted twin and adoption studies to reach this goal. However what was found was; genes or heredity is not the sole reason for alcoholism, along with it […]

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Impact of alcoholism on family

Alcoholism is a well known health hazard. It impacts the individual’s health, their social status, finance and mental health too. But along with these it also affects the abuser’s family. Man is a social being and is always connected to others; the closet among all is family. Hence the family is bound to get an […]

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Alcohol withdrawal Syndrome

Alcohol withdrawal Syndrome are a group of symptoms that are life threatening and occur when an individual completely stops consuming alcohol or greatly reduces their intake after a long period of alcohol intake. These symptoms may start from 8 hours to days after the individual stops and may last for day or even weeks. When […]

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Obsessive compulsive disorder-...

“An individual looking as normal as person can be, has an ordinary simple job and lives an ordinary life. But when it comes to having meals this individual has rules; the fork has to be on the right and spoon on the left straight, salt always on the right side of the plate, food has […]

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Tricyclic Antidepression Drugs May Harm Health More Than Treating Depression

Tricyclic antidepressants such as amitriptyline, desipramine, and doxepin, may harm your heart, according to a new study conducted by researchers at University College London (UCL). This risk may extend beyond individuals who are being treated for depression, as these older antidepressants are also used to treat anxiety, sleep problems, headache, and back pain, among other conditions.
Although tricyclic antidepressants are one of the oldest classes of antidepressants, they are still used extensively, according to eMedExpert. Today, selective serotonin reuptake inhibitors (SSRIs) have replaced tricyclics as the treatment of choice for depressive disorders, primarily because patients tolerate them better and they are safer if taken in excess.
Researchers at University College London compared the use of tricyclic antidepressants with SSRIs or no antidepressant use in nearly 15,000 individuals in Scotland. Overall, the older antidepressants were linked with a 35 percent increased risk of cardiovascular disease, while use of SSRIs was not.
Based on these findings, Dr. Mark Hamer, senior research fellow in the Department of Epidemiology and Public Health at UCL remarked that they “suggest that there is an association between the use of tricyclic antidepressants and an increased risk of CVD that is not explained by existing mental illness.” The study results thus indicate that tricyclics have properties that are responsible for the greater risk.
Previous research has shown tricyclic use to be associated with a significantly higher rate of serious cardiovascular side effects, such as increased heart rate, as well as arrhythmias, blood pressure abnormalities, and congestive heart failure. They have also been linked with weight gain and diabetes, which are risk factors for cardiovascular disease.
The UCL study’s authors note that other factors may be involved in the possible link between tricyclic antidepressant use and cardiovascular disease. Hamer pointed out that individuals who take antidepressants are more likely to be overweight, smoke, and not get sufficient exercise, also risk factors for cardiovascular disease.
Before it can be determined with more certainty that tricyclic antidepressants can harm the heart, “there needs to be more research looking closely at the effects of these drugs on your heart,” notes Amy Thompson, senior cardiac nurse at the British Heart Foundation. Because antidepressants help a great many people, “it would be unwise for anyone taking them to stop based on the results of this study alone.”

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