Borderline Personality Disorde...

Borderline personality disorder (BPD) is a serious mental health issue manifest by continuous unsteadiness in moods, behaviour, functioning and self-image. These experiences frequently result in unstable relationships and impulsive action. An individual with BPD may meet extreme scenes of anger, misery, and uneasiness that may last from just a couple of hours to days. Borderline […]

Read more
Alternative text

Substance Abuse Statistics

Substance abuse means to the harmful or unsafe use of psychoactive substances, including illicit drugs and alcohol. Psychoactive substance use can prompt to dependence disorder; a group of behavioural, physiological, cognitive phenomenon that create after frequent substance use and that normally incorporate a powerful urge to take the drug, challenges in controlling its use, holding […]

Read more
Alternative text

Borderline Personality Disorde...

Borderline personality disorder or BPD is mostly known to occur among women and rarely seen in men. It is a disorder that characterizes high emotionality, sensitivity and unstable patterns of relationships. Men express BPD symptoms differently from women, this is one of the reasons it gets misunderstood. It has been suggested by studies that women […]

Read more
Alternative text

Substance Abuse Disorder

Substance abuse disorder is when an individual engages in a harmful intake of a substance or drug, affecting various areas of life. Due to the substance abuse the individual fails to function effectively in their personal, professional and social areas of life. Identifying the symptoms at an early stage can enable a quicker recovery. Here […]

Read more
Alternative text

Borderline Personality Disorde...

Do you have someone in your life who, most of the time, have terrible mood fluctuations, multiple unstable relationships, always feel empty and impulsive? Are these affecting their personal and professional life? You may consider seeking a professional opinion as these are primary symptoms of borderline personality disorder or BPD. Here are few questions that […]

Read more
Alternative text

Tricyclic Antidepression Drugs May Harm Health More Than Treating Depression

Tricyclic antidepressants such as amitriptyline, desipramine, and doxepin, may harm your heart, according to a new study conducted by researchers at University College London (UCL). This risk may extend beyond individuals who are being treated for depression, as these older antidepressants are also used to treat anxiety, sleep problems, headache, and back pain, among other conditions.
Although tricyclic antidepressants are one of the oldest classes of antidepressants, they are still used extensively, according to eMedExpert. Today, selective serotonin reuptake inhibitors (SSRIs) have replaced tricyclics as the treatment of choice for depressive disorders, primarily because patients tolerate them better and they are safer if taken in excess.
Researchers at University College London compared the use of tricyclic antidepressants with SSRIs or no antidepressant use in nearly 15,000 individuals in Scotland. Overall, the older antidepressants were linked with a 35 percent increased risk of cardiovascular disease, while use of SSRIs was not.
Based on these findings, Dr. Mark Hamer, senior research fellow in the Department of Epidemiology and Public Health at UCL remarked that they “suggest that there is an association between the use of tricyclic antidepressants and an increased risk of CVD that is not explained by existing mental illness.” The study results thus indicate that tricyclics have properties that are responsible for the greater risk.
Previous research has shown tricyclic use to be associated with a significantly higher rate of serious cardiovascular side effects, such as increased heart rate, as well as arrhythmias, blood pressure abnormalities, and congestive heart failure. They have also been linked with weight gain and diabetes, which are risk factors for cardiovascular disease.
The UCL study’s authors note that other factors may be involved in the possible link between tricyclic antidepressant use and cardiovascular disease. Hamer pointed out that individuals who take antidepressants are more likely to be overweight, smoke, and not get sufficient exercise, also risk factors for cardiovascular disease.
Before it can be determined with more certainty that tricyclic antidepressants can harm the heart, “there needs to be more research looking closely at the effects of these drugs on your heart,” notes Amy Thompson, senior cardiac nurse at the British Heart Foundation. Because antidepressants help a great many people, “it would be unwise for anyone taking them to stop based on the results of this study alone.”

Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>

DO YOU HAVE ANY ENQUIRIES ?